Select Committee on Science and Technology Minutes of Evidence



Supplementary memorandum submitted by Dr Arpad Pusztai

  It is not my intention to use this forum as the means of airing the dispute between myself and RRI. For that reason I had previously limited my submission to the Committee so far as it related to that matter. What is at stake here, however, is the validity and freedom of the scientific process, as demonstrated by the treatment to which I have been subjected. It is to correct mis-statements made in regard to this process, that I am submitting this further paper.

1.  Precise nature of RRI experiments

  It was never part of the experimental process at RRI to involve feeding GM potatoes with the lectin PHA whether from red kidney beans or otherwise, nor the lectin ConA. The only lectin involved in our experiments was GNA.

2.  The "ConA" muddle

  There was never any misunderstanding by me as to the non-involvement of ConA in the experiments we were conducting. All my statements related specifically to GNA GM-potatoes. It is evident that Professor James thought otherwise, as appears from the Press Release of 10 August 1998 issued wholly without reference to me (Appendix 2 in my earlier Memorandum dated 1 March 1999)[5]. This was also apparent from changes he proposed to a letter he had requested I draft to Mr Wotherspoon of MAFF. I do not know if the letter was sent and in what form. It is clear that he subsequently recognised his mistake, shown by the Press Release of 12 August 1998. He represented that error, however, as one for which I was responsible. That emphatically is not the case.

3.  Other misconceptions

    —  The 110 day GNA immune studies with the parent and GM-potatoes were already completed and calculated when the "World in Action" programme was recorded (24 June 1998). See pages 46 and 47 of the Audit Report (copies annexed)[5];

    —  The suggestion that "Dr Pusztai and his assistants agreed that the growth impairment" had not been found in the 110 day feeding studies; that is totally at variance with our findings. Although the growth rate of rats fed the parent and the GM-potatoes, was apparently the same in a particular study, it was one in which a 20 per cent increase in protein was deliberately provided to compensate for the growth impairment.

4.  "World in Action"

  The programme was recorded in the presence of the PR to RRI some 7 weeks prior to the actual broadcast. The approved RRI approach to GM safety issues, was one of caution. It was proposed that I should participate in the programme because of the direct part I had in the relevant experimentation and study. In expressing the RRI cautionary approach, it followed that in the programme I stated that there were concerns. When pressed as to the concerns, I referred to the tests I had conducted, making the point that further evidence was needed.

  As to the "Frontline Scotland" programme, I had no part in it.

5.  Publication of Reports

  The Audit Report was presented to the House of Lords by Professor James on 28 October 1998 at which time my Alternative Report was available, in which I contested many of the conclusions. For purposes of balance, one needed to be considered in conjunction with the other but that opportunity was not given.

6.  Suspension and subsequent events

  Professor James in his presentation to the House of Lords expressly stated that there was no questionof any malpractice on my part, making the kind observation that "we did not expect that remotely withDr Pusztai, of such prestige and known to be so scientifically rigorous". Nevertheless, he used an MRC procedure to effect my suspension which is only appropriate for use when there is malpractice. By doing so, RRI created the impression that I had in some fashion been guilty of such an act. That was highly damaging to my scientific reputation and put the credibility of my work in doubt.

  It had always been the understanding that I would continue at RRI until the conclusion of my programmes, expected in mid 2000. I had never agreed to earlier retirement.

  I have no arrangement with the RRI to continue as a consultant (none has been offered) and there are no measures to protect my financial interests as suggested by Professor James. All personnel and working facilities were withdrawn from me on 12 August and persisted until my forced retirement. Professor James' letters to me of 18 and 20 August 1998 (copies annexed)* set out in detailed form the legal and practical limitations which he stated applied to me with emphatic warnings as to the consequences if I failed to observe them. None of this was at all conducive to any continuing involvement in the programmes, with which I had been so actively connected throughout.

  Since leaving RRI, I have had to manage on my own.

CONCLUSIONS

  Our data are neither crude nor preliminary. They are the intitial results of carefully designed and conducted studies which have now been fully verified by independent statistical analysis which justify our claims that the expression of GNA gene in potatoes do affect the nutritional value of the potatoes and that the organ development and immune system's responsiveness of rat fed on diets containing these potatoes, suffer significant damage.

8 March 1999


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